Bone Marrow Homeostasis Is Impaired via JAK/STAT and Glucocorticoid Signaling in Cancer Cachexia Model

Bone Marrow Homeostasis Is Impaired via JAK/STAT and Glucocorticoid Signaling in Cancer Cachexia Model

Cancer cachexia is a multifactorial systemic inflammation disease caused by complex interactions between the tumor and host tissues via soluble factors. However, whether cancer cachexia affects the bone marrow, in particular the hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs), rema...

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Bibliographic Details
Main Authors: Jinyeong Yu, Sanghyuk Choi, Aran Park, Jungbeom Do, Donghyun Nam, Youngjae Kim, Jinok Noh, Kil Yeon Lee, Chi Hoon Maeng, Ki-Sook Park
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
cancer cachexia
bone marrow
mesenchymal stem cells
JAK
STAT3
glucocorticoid
Online Access:https://www.mdpi.com/2072-6694/13/5/1059

Internet

https://www.mdpi.com/2072-6694/13/5/1059

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