Differential effect of sleep deprivation on place cell representations, sleep architecture, and memory in young and old mice

Summary: Poor sleep quality is associated with age-related cognitive decline, and whether reversal of these alterations is possible is unknown. In this study, we report how sleep deprivation (SD) affects hippocampal representations, sleep patterns, and memory in young and old mice. After training in...

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Bibliographic Details
Main Authors: Robin K. Yuan, Matthew R. Lopez, Manuel-Miguel Ramos-Alvarez, Marc E. Normandin, Arthur S. Thomas, David S. Uygun, Vanessa R. Cerda, Amandine E. Grenier, Matthew T. Wood, Celia M. Gagliardi, Herminio Guajardo, Isabel A. Muzzio
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721005933