ALCAM Mediates DC Migration Through Afferent Lymphatics and Promotes Allospecific Immune Reactions

ALCAM Mediates DC Migration Through Afferent Lymphatics and Promotes Allospecific Immune Reactions

Activated leukocyte cell adhesion molecule (ALCAM, CD166) is a cell adhesion molecule of the immunoglobulin superfamily and has been implicated in diverse pathophysiological processes including T cell activation, leukocyte trafficking, and (lymph)angiogenesis. However, exploring the therapeutic pote...

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Bibliographic Details
Main Authors: Ann-Helen Willrodt, Ann-Charlott Salabarria, Philipp Schineis, Desislava Ignatova, Morgan Campbell Hunter, Martina Vranova, Alexandra M. Golding-Ochsenbein, Elena Sigmund, Annatina Romagna, Verena Strassberger, Marina Fabbi, Silvano Ferrini, Claus Cursiefen, Dario Neri, Emmanuella Guenova, Felix Bock, Cornelia Halin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
ALCAM
dendritic Cell (DC)
lymphatic vessel
lymphangiogenesis
DC migration
cornea
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00759/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00759/full

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