Effect of bile acids on the expression of MRP3 and MRP4: An In vitro study in HepG2 cell line

Introduction and objectives: Free and conjugated bile acids (BA's) cannot cross cell membranes; therefore, a particular transport system is required by the cell. Members of the family of ABC (ATP-binding proteins) transporters transfer bile acids in and out of the cell, preventing their accumul...

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Bibliographic Details
Main Authors: Suilma Ivette Pérez-Pineda, Lidia Baylón-Pacheco, Patricia Espíritu-Gordillo, Victor Tsutsumi, José Luis Rosales-Encina
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Annals of Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268121000247