Cholesterol sulfate stimulates involucrin transcription in keratinocytes by increasing Fra-1, Fra-2, and Jun D

Cholesterol sulfate stimulates involucrin transcription in keratinocytes by increasing Fra-1, Fra-2, and Jun D

Lipids that are synthesized de novo in the epidermis, including fatty acids, oxysterols, 1,25-dihydroxyvitamin D3, and farnesol, can regulate the differentiation of normal human keratinocytes (NHK). Cholesterol sulfate (CS), an epidermal lipid that is produced in the upper nucleated layers of the ep...

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Bibliographic Details
Main Authors: Karen Hanley, Ladonna Wood, Dean C. Ng, Shan Shan He, Peggy Lau, Arthur Moser, Peter M. Elias, Daniel D. Bikle, Mary L. Williams, Kenneth R. Feingold
Format: Article
Language:English
Published: Elsevier 2001-03-01
Series:Journal of Lipid Research
Subjects:
transglutaminase
cornified envelope
differentiation
AP-1
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520316631

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http://www.sciencedirect.com/science/article/pii/S0022227520316631

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