Mass spectrometry-based analysis of cerebrospinal fluid from arthritis patients—immune-related candidate proteins affected by TNF blocking treatment

Mass spectrometry-based analysis of cerebrospinal fluid from arthritis patients—immune-related candidate proteins affected by TNF blocking treatment

Abstract Background Signs of inflammation in cerebrospinal fluid (CSF) of rheumatoid arthritis patients correlate positively with fatigue, a central nervous system (CNS)-related symptom that can be partially suppressed by TNF blockade. This suggests a possible role for CNS inflammation in arthritis...

Full description

Bibliographic Details
Main Authors: Johanna Estelius, Johan Lengqvist, Elena Ossipova, Helena Idborg, Erwan Le Maître, Magnus L. A. Andersson, Lou Brundin, Mohsen Khademi, Elisabet Svenungsson, Per-Johan Jakobsson, Jon Lampa
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Arthritis Research & Therapy
Subjects:
Chronic inflammation
CSF
Intrathecal inflammation
Anti-TNF
Proteomics
Ankylosing spondylitis
Online Access:http://link.springer.com/article/10.1186/s13075-019-1846-6

Internet

http://link.springer.com/article/10.1186/s13075-019-1846-6

Similar Items