Cytotoxic Sesquiterpenoid Quinones and Quinols, and an 11-Membered Heterocycle, Kauamide, from the Hawaiian Marine Sponge <i>Dactylospongia elegans</i>

Cytotoxic Sesquiterpenoid Quinones and Quinols, and an 11-Membered Heterocycle, Kauamide, from the Hawaiian Marine Sponge <i>Dactylospongia elegans</i>

Several known sesquiterpenoid quinones and quinols (<b>1</b>&#8722;<b>9</b>), and kauamide (<b>10</b>), a new polyketide-peptide containing an 11-membered heterocycle, were isolated from the extracts of the Hawaiian marine sponge <i>Dactylospongia</i&...

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Bibliographic Details
Main Authors: Ram P. Neupane, Stephen M. Parrish, Jayanti Bhandari Neupane, Wesley Y. Yoshida, M. L. Richard Yip, James Turkson, Mary Kay Harper, John D. Head, Philip G. Williams
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Marine Drugs
Subjects:
sesquiterpenoid quinones
11-membered heterocycle
<i>Dactylospongia elegans</i>
DFT computations
BACE1
human glioma
human pancreatic carcinoma
Online Access:https://www.mdpi.com/1660-3397/17/7/423

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https://www.mdpi.com/1660-3397/17/7/423

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