An investigation of the auto-induction of and gender-related variability in the pharmacokinetics of dihydroartemisinin in the rat

<p>Abstract</p> <p>Background</p> <p>Artemisinin (QHS) and its derivatives dihydroartemisinin (DHA), artemether and artesunate have become the first-line anti-malarials in areas of multidrug resistance. Declining plasma concentrations during the repeated dosing have bee...

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Bibliographic Details
Main Authors: Zhu Fanping, Du Fuying, Li Xinxiu, Xing Jie
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Malaria Journal
Subjects:
Online Access:http://www.malariajournal.com/content/11/1/379