Effectiveness of 23-Valent Polysaccharide Pneumococcal Vaccine and Changes in Invasive Pneumococcal Disease Incidence from 2000 to 2017 in Those Aged 65 and Over in England and Wales

Background: Invasive Pneumococcal Disease (IPD) is a major public health concern. The effectiveness of 23-valent polysaccharide pneumococcal vaccine (PPV23) against IPD in older age-groups is not fully understood. We measured PPV23 effectiveness against IPD and interpreted changes in IPD incidence b...

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Bibliographic Details
Main Authors: Abdelmajid Djennad, Mary E. Ramsay, Richard Pebody, Norman K. Fry, Carmen Sheppard, Shamez N. Ladhani, Nick J. Andrews
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:EClinicalMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537018300622