Analysis of compositions of microbiomes with bias correction

Differential abundance analysis of microbiome data continues to be challenging due to data complexity. The authors propose a method which estimates the unknown sampling fractions and corrects the bias induced by their differences among samples.

Bibliographic Details
Main Authors: Huang Lin, Shyamal Das Peddada
Format: Article
Language:English
Published: Nature Publishing Group 2020-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17041-7