The Dilemma Of TP53 Codon 72 Polymorphism (Rs1042522) And Breast Cancer Risk: A Case-Control Study And Meta-Analysis In The Iranian Population

The Dilemma Of TP53 Codon 72 Polymorphism (Rs1042522) And Breast Cancer Risk: A Case-Control Study And Meta-Analysis In The Iranian Population

Objective Mutations of TP53 as a tumor suppressor gene are frequently observed in different types of cancer. A codon 72 polymorphism located on exon 4 with two alleles encoding either Proline (CCC) or Arginine (CGC) has been indicated as a common variation in association with cancers. Controversial...

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Bibliographic Details
Main Authors: Fahimeh Afzaljavan, Negin Chaeichi Tehrani, Mahdi Rivandi, Saeed Zarif Ghasemian, Elham Vahednia, Reza Khayami, Mohammad Abavisani, Alireza Pasdar
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2020-07-01
Series:Cell Journal
Subjects:
breast cancer
genetic variation
polymorphism
tp53
Online Access:https://celljournal.org/journal/article/fulltext/the-dilemma-of-tp53-codon-72-polymorphism-rs1042522-and-breast-cancer-risk-a-case-control-study-and-meta-analysis-in-iranian-population.pdf

Internet

https://celljournal.org/journal/article/fulltext/the-dilemma-of-tp53-codon-72-polymorphism-rs1042522-and-breast-cancer-risk-a-case-control-study-and-meta-analysis-in-iranian-population.pdf

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