Xenogeneic transplantation of human adipose-derived stem cell sheets accelerate angiogenesis and the healing of skin wounds in a Zucker Diabetic Fatty rat model of obese diabetes

Xenogeneic transplantation of human adipose-derived stem cell sheets accelerate angiogenesis and the healing of skin wounds in a Zucker Diabetic Fatty rat model of obese diabetes

Introduction: Diabetic patients with foot ulcers often suffer impaired wound healing due to diabetic neuropathy and blood flow disturbances. Direct injection of human adipose-derived stem cells (hASCs) effectively accelerates wound healing, although hASCs are relatively unstable. Methods: We develop...

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Bibliographic Details
Main Authors: Mariko Hamada, Takanori Iwata, Yuka Kato, Kaoru Washio, Shunichi Morikawa, Hiroyuki Sakurai, Masayuki Yamato, Teruo Okano, Yasuko Uchigata
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Regenerative Therapy
Subjects:
Diabetic foot ulcers
Adipose-derived stem cell
Cell sheet
Wound healing
Xenogeneic transplantation
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320416300724

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http://www.sciencedirect.com/science/article/pii/S2352320416300724

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