Intratumoral Heterogeneity Determines the Expression of mTOR-pathway Proteins in Prostate Cancer

The aim of this study was to evaluate the expression of mammalian target of rapamycin (mTOR), phosphorylated-mTOR (p-mTOR), and eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) in prostate cancer (PCa) in order to assess intratumoral heterogeneity and correlation with clinicopa...

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Bibliographic Details
Main Authors: Giorgio Ivan Russo, Jörg Hennenlotter, Ulrich Vogel, Ursula Kühs, Thomas Manfred Wurm, Valentina Gerber, Tim Neumann, Sebastiano Cimino, Arnulf Stenzl, Tilman Todenhöfer
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2019/1296865