Consequent stages of developing a multi-compartmental mechanistic model for chronically inhaled nanoparticles pulmonary retention

The paper retraces the development of a mechanistic multicompartmental system model describing particle retention in lungs under chronic inhalation exposures. This model was first developed and experimentally tested for various conditions of exposure to polydisperse dusts of SiO2 or TiO2. Later on i...

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Bibliographic Details
Main Authors: Boris A. Katsnelson, Marina P. Sutunkova, Ludmila K. Konysheva, Svetlana N. Solovyeva, Ilzira A. Minigalieva, Vladimir B. Gurvich, Larissa I. Privalova
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Toxicology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750019301295