Modulated Zika virus NS1 conjugate offers advantages for accurate detection of Zika virus specific antibody in double antigen binding and Ig capture enzyme immunoassays.

The accurate diagnosis and seroprevalence investigations of Zika virus (ZKV) infections remain complex due to cross reactivity with other flaviviruses. Two assay formats, both using labelled Zika virus NS1 antigen as a revealing agent (a double antigen binding assay, DABA, and an immunoglobulin Ig c...

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Bibliographic Details
Main Authors: Richard S Tedder, Steve Dicks, Samreen Ijaz, Nathalia Caroline Santiago de Souza, Anderson Vincente de Paula, Flavia Levy, Raquel Medialdea-Carrera, José Eduardo Levi, Claudio S Pannuti, Patrícia Carvalho de Sequeira, David W G Brown, Ines Ushiro Lumb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215708