Functional polymorphisms in asporin and CILP together with joint loading predispose to hand osteoarthritis

Functional polymorphisms in asporin and CILP together with joint loading predispose to hand osteoarthritis

Abstract Background Osteoarthritis (OA) is the most common degenerative joint disease afflicting people in the Western world and has a strong genetic influence. The aim of this study was to examine the association of two known functional polymorphisms in the TGF-β inhibiting genes, asporin (ASPN) an...

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Bibliographic Details
Main Authors: Mari Taipale, Svetlana Solovieva, Päivi Leino-Arjas, Minna Männikkö
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Genetics
Subjects:
Osteoarthritis
Asporin
Cartilage intermediate layer protein
Genetic association
Functional variant
Online Access:http://link.springer.com/article/10.1186/s12863-017-0585-4

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http://link.springer.com/article/10.1186/s12863-017-0585-4

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