A new and simple non-chromatographic method for isolation of drug/linker constructs: vc-MMAE evaluation
Introduction: Auristatin and its derivatives (synthetic analogues of dolastatin 10, an antineoplastic natural product), are highly potent antimitotic agents which have attracted considerable attention because of their cytotoxic activity when targeting tumor cells in the form of antibody-drug conjuga...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nikan Research Institute
2017-10-01
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| Series: | Journal of HerbMed Pharmacology |
| Subjects: | |
| Online Access: | http://herbmedpharmacol.com/PDF/JHP_20170924171003 |