Effect of small interfering RNAs on matrix metalloproteinase 1 expression

Three small double strand siRNAs (506-MMP1, 859-MMP1 and 891-MMP1), each contains 25–26 nucleotides, with high specific to human MMP1 were designed according to mRNA sequence of human MMP1 (NCBI, NM_002421). To monitor the MMP1 gene expression, the total RNAs of human skin fibroblast (Detroit 551, B...

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Bibliographic Details
Main Authors: Gen-Hung Chen, Chun-Hua Huang, Huang-Yao Luo, Shann-Tzong Jiang
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Biotechnology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2215017X14000265