Nanobodies targeting norovirus capsid reveal functional epitopes and potential mechanisms of neutralization.

Norovirus is the leading cause of gastroenteritis worldwide. Despite recent developments in norovirus propagation in cell culture, these viruses are still challenging to grow routinely. Moreover, little is known on how norovirus infects the host cells, except that histo-blood group antigens (HBGAs)...

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Bibliographic Details
Main Authors: Anna D Koromyslova, Grant S Hansman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5667739?pdf=render