Insights into the Mn<sup>2+</sup> Binding Site in the Agmatinase-Like Protein (ALP): A Critical Enzyme for the Regulation of Agmatine Levels in Mammals

Insights into the Mn<sup>2+</sup> Binding Site in the Agmatinase-Like Protein (ALP): A Critical Enzyme for the Regulation of Agmatine Levels in Mammals

Agmatine is a neurotransmitter with anticonvulsant, anti-neurotoxic and antidepressant-like effects, in addition it has hypoglycemic actions. Agmatine is converted to putrescine and urea by agmatinase (AGM) and by an agmatinase-like protein (ALP), a new type of enzyme which is present in human and r...

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Bibliographic Details
Main Authors: María-Belen Reyes, José Martínez-Oyanedel, Camila Navarrete, Erika Mardones, Ignacio Martínez, Mónica Salas, Vasthi López, María García-Robles, Estefania Tarifeño-Saldivia, Maximiliano Figueroa, David García, Elena Uribe
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
ureohydrolase
ALP
manganese
Online Access:https://www.mdpi.com/1422-0067/21/11/4132

Internet

https://www.mdpi.com/1422-0067/21/11/4132

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