Bioengineering of injectable encapsulated aggregates of pluripotent stem cells for therapy of myocardial infarction

Stem cell therapy of myocardial infarction is hampered by poor survival of injected cells. Here the authors develop injectable aggregates of stem cells differentiated to an early cardiac stage and encapsulated in a biodegradable micromatrix, and show their enhanced therapeutic efficacy in a heart in...

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Bibliographic Details
Main Authors: Shuting Zhao, Zhaobin Xu, Hai Wang, Benjamin E. Reese, Liubov V. Gushchina, Meng Jiang, Pranay Agarwal, Jiangsheng Xu, Mingjun Zhang, Rulong Shen, Zhenguo Liu, Noah Weisleder, Xiaoming He
Format: Article
Language:English
Published: Nature Publishing Group 2016-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13306