In Search of Effective Treatments Targeting α-Synuclein Toxicity in Synucleinopathies: Pros and Cons

In Search of Effective Treatments Targeting α-Synuclein Toxicity in Synucleinopathies: Pros and Cons

Parkinson’s disease (PD), multiple system atrophy (MSA) and Dementia with Lewy bodies (DLB) represent pathologically similar, progressive neurodegenerative disorders characterized by the pathological aggregation of the neuronal protein α-synuclein. PD and DLB are characterized by the abnormal accumu...

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Bibliographic Details
Main Authors: Maria Fouka, Panagiota Mavroeidi, Grigoria Tsaka, Maria Xilouri
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
α-synuclein
autophagy
immunotherapy
propagation
protein aggregation
proteasome
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.559791/full

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https://www.frontiersin.org/article/10.3389/fcell.2020.559791/full

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