A knockout cell library of GPI biosynthetic genes for functional studies of GPI-anchored proteins

A knockout cell library of GPI biosynthetic genes for functional studies of GPI-anchored proteins

Liu et al. construct a knock out cell library of genes involved in the biosynthesis of glycosylphosphatidylinositol (GPI)-anchored protein (GPI-APs) from HEK-293 cells and analyzed the surface expression and sensitivity to phosphatidylinositol-specific phospholipase C. Furthermore, the authors also...

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Bibliographic Details
Main Authors: Si-Si Liu, Yi-Shi Liu, Xin-Yu Guo, Yoshiko Murakami, Ganglong Yang, Xiao-Dong Gao, Taroh Kinoshita, Morihisa Fujita
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02337-1

Internet

https://doi.org/10.1038/s42003-021-02337-1

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