Changes in cell shape and desmin intermediate filament distribution are associated with down-regulation of desmin expression in C2C12 myoblasts grown in the absence of extracellular Ca2+

Changes in cell shape and desmin intermediate filament distribution are associated with down-regulation of desmin expression in C2C12 myoblasts grown in the absence of extracellular Ca2+

Desmin is the main intermediate filament (IF) protein of muscle cells. In skeletal muscle, desmin IFs form a scaffold that interconnects the entire contractile apparatus with the subsarcolemmal cytoskeleton and cytoplasmic organelles. The interaction between desmin and the sarcolemma is mediated by...

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Bibliographic Details
Main Authors: C.S. Mermelstein, L.M. Amaral, M.I.L. Rebello, J.S.N. Reis, R. Borojevic, M.L. Costa
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2005-07-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Extracellular Ca2+, EGTA
Myoblasts
Desmin
Intermediate filaments
RT-PCR
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000700005

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000700005

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