Propofol pretreatment attenuates lipopolysaccharide-induced acute lung injury in rats by activating the phosphoinositide-3-kinase/Akt pathway

The aim of this study was to investigate the effect of propofol pretreatment on lipopolysaccharide (LPS)-induced acute lung injury (ALI) and the role of the phosphoinositide-3-kinase/protein kinase B (PI3K/Akt) pathway in this procedure. Survival was determined 48 h after LPS injection. At 1 h after...

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Bibliographic Details
Main Authors: L.L. Zhao, G.C. Hu, S.S. Zhu, J.F. Li, G.J. Liu
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2014-12-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014001201062&lng=en&tlng=en