Generation and characterization of transgenic mice expressing mitochondrial targeted red fluorescent protein selectively in neurons: modeling mitochondriopathy in excitotoxicity and amyotrophic lateral sclerosis

<p>Abstract</p> <p>Background</p> <p>Mitochondria have roles or appear to have roles in the pathogenesis of several chronic age-related and acute neurological disorders, including Charcot-Marie-Tooth disease, amyotrophic lateral sclerosis, Parkinson's disease, and...

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Bibliographic Details
Main Authors: Wang Yi, Pan Yan, Price Ann, Martin Lee J
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Molecular Neurodegeneration
Subjects:
Online Access:http://www.molecularneurodegeneration.com/content/6/1/75