Human Blood CD1c+ Dendritic Cells Promote Th1 and Th17 Effector Function in Memory CD4+ T Cells

Dendritic cells (DC) initiate the differentiation of CD4+ helper T cells into effector cells including Th1 and Th17 responses that play an important role in inflammation and autoimmune disease pathogenesis. In mice, Th1 and Th17 responses are regulated by different conventional (c) DC subsets, with...

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Bibliographic Details
Main Authors: Ingrid M. Leal Rojas, Wai-Hong Mok, Frances E. Pearson, Yoshihito Minoda, Tony J. Kenna, Ross T. Barnard, Kristen J. Radford
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Immunology
Subjects:
Th1
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00971/full