Coenzyme Q10 attenuates lung and liver fibrosis via modulation of autophagy in methotrexate treated rat

The present study was conducted to investigate the potential protective effects of coenzyme Q 10 (CoQ10) administration on methotrexate induced lung and liver fibrosis in rat model, and to explore our hypothesis regarding its possible mechanism of action through reactivation of autophagy pathway. Me...

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Bibliographic Details
Main Authors: Doaa I. Mohamed, Eman Khairy, Sherin Shafik Tawfek, Eman K. Habib, Marwa A. Fetouh
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S075333221834873X