Klotho and Aminopeptidases as Early Biomarkers of Renal Injury in Zucker Obese Rats

Klotho and Aminopeptidases as Early Biomarkers of Renal Injury in Zucker Obese Rats

The aim of this study was to investigate if urinary glutamyl aminopeptidase (GluAp), alanyl aminopeptidase (AlaAp), Klotho and hydroxyproline can be considered as potential biomarkers of renal injury and fibrosis in an experimental model of obesity. Male Zucker lean (ZL) and obese (ZO) rats were stu...

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Bibliographic Details
Main Authors: Sebastián Montoro-Molina, Antonio López-Carmona, Andrés Quesada, Francisco O’Valle, Natividad Martín-Morales, Antonio Osuna, Félix Vargas, Rosemary Wangensteen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Physiology
Subjects:
Zucker rats
aminopeptidases
Klotho
hydroxyproline
renal injury
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01599/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.01599/full

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