Significance of somatic mutations and content alteration of mitochondrial DNA in esophageal cancer

<p>Abstract</p> <p>Background</p> <p>The roles of mitochondria in energy metabolism, the generation of ROS, aging, and the initiation of apoptosis have implicated their importance in tumorigenesis. In this study we aim to establish the mutation spectrum and to understan...

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Bibliographic Details
Main Authors: Wang Yu-Fen, Bai Ren-Kui, Liu Ling-Ling, Chang Julia, Tan Duan-Jun, Yeh Kun-Tu, Wong Lee-Jun C
Format: Article
Language:English
Published: BMC 2006-04-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/6/93