Chromatin accessibility plays a key role in selective targeting of Hox proteins

Abstract Background Hox transcription factors specify segmental diversity along the anterior-posterior body axis in metazoans. While the different Hox family members show clear functional specificity in vivo, they all show similar binding specificity in vitro and a satisfactory understanding of in v...

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Bibliographic Details
Main Authors: Damiano Porcelli, Bettina Fischer, Steven Russell, Robert White
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Genome Biology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13059-019-1721-4