Myeloid-derived suppressor cells are bound and inhibited by anti-thymocyte globulin

Myeloid-derived suppressor cells (MDSCs) inhibit T cell responses and are relevant to cancer, autoimmunity and transplant biology. Anti-thymocyte globulin (ATG) is a commonly used T cell depletion agent, yet the effect of ATG on MDSCs has not been investigated. MDSCs were generated in Lewis Lung Car...

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Bibliographic Details
Main Authors: Young Suk Lee, Eduardo Davila, Tianshu Zhang, Hugh P Milmoe, Stefanie N Vogel, Jonathan S Bromberg, Joseph R Scalea
Format: Article
Language:English
Published: SAGE Publishing 2019-01-01
Series:Innate Immunity
Online Access:https://doi.org/10.1177/1753425918820427