Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo

Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo

Abstract Background Polyphyllin VII (PP7), a steroidal saponin from P. polyphylla has been found to exert strong anticancer activity. Little is known about the anti-angiogenesis and anti-metastasis properties of PP7. In this study, the anti-angiogenic and anti-metastatic effects of PP7 on HCC and th...

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Bibliographic Details
Main Authors: Chao Zhang, Qingrui Li, Guozheng Qin, Yi Zhang, Chaoying Li, Liwen Han, Rongchun Wang, Shudan Wang, Haixia Chen, Kechun Liu, Chengwei He
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Chinese Medicine
Subjects:
Polyphyllin VII
Hepatocellular carcinoma cells
Anti-angiogenesis
Anti-metastasis
NF-κB/MMP-9/VEGF pathway
Online Access:https://doi.org/10.1186/s13020-021-00447-w

Internet

https://doi.org/10.1186/s13020-021-00447-w

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