Dia2 controls transcription by mediating assembly of the RSC complex.

BACKGROUND:Dia2 is an F-box protein found in the budding yeast, S. cerevisiae. Together with Skp1 and Cul1, Dia2 forms the substrate-determining part of an E3 ubiquitin ligase complex, otherwise known as the SCF. Dia2 has previously been implicated in the control of replication and genome stability...

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Bibliographic Details
Main Authors: Edward J Andress, Roman Holic, Mariola J Edelmann, Benedikt M Kessler, Veronica P C C Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3118812?pdf=render