Betulinic Acid Derivatives NVX-207 and B10 for Treatment of Glioblastoma—An in Vitro Study of Cytotoxicity and Radiosensitization

Betulinic Acid Derivatives NVX-207 and B10 for Treatment of Glioblastoma—An in Vitro Study of Cytotoxicity and Radiosensitization

Betulinic acid (BA), a pentacyclic triterpene, represents a new therapeutic substance that has potential benefits for treating glioblastoma. Recently, new strategies for producing BA derivatives with improved properties have evolved. However, few studies have examined the combination of BA or BA der...

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Bibliographic Details
Main Authors: Matthias Bache, Stephan Bernhardt, Sarina Passin, Henri Wichmann, Anja Hein, Martin P Zschornak, Matthias Kappler, Helge Taubert, Reinhard Paschke, Dirk Vordermark
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:International Journal of Molecular Sciences
Subjects:
betulinic acid derivatives
glioma
cytotoxicity
irradiation
normoxia
hypoxia
Online Access:http://www.mdpi.com/1422-0067/15/11/19777

Internet

http://www.mdpi.com/1422-0067/15/11/19777

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