Nicotine stimulates collagen type I expression in lung via α7 nicotinic acetylcholine receptors

Nicotine stimulates collagen type I expression in lung via α7 nicotinic acetylcholine receptors

Abstract Background Tobacco-related chronic lung diseases are characterized by alterations in lung architecture leading to decreased lung function. Knowledge of the exact mechanisms involved in tobacco-induced tissue remodeling and inflammation remains incomplete. We hypothesize that nicotine stimul...

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Bibliographic Details
Main Authors: Glenn W. Vicary, Jeffrey D. Ritzenthaler, Tanmay S. Panchabhai, Edilson Torres-González, Jesse Roman
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Respiratory Research
Subjects:
Tobacco
Nicotine
Lung
Matrix
Integrin
Tissue remodeling
Online Access:http://link.springer.com/article/10.1186/s12931-017-0596-8

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http://link.springer.com/article/10.1186/s12931-017-0596-8

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