Comprehensive characterization and clinical relevance of the SWI/SNF copy number aberrations across human cancers

Comprehensive characterization and clinical relevance of the SWI/SNF copy number aberrations across human cancers

Abstract Background Alterations in genes encoding chromatin regulatory proteins are prevalent in cancers and may confer oncogenic properties and molecular changes linked to therapy resistance. However, the impact of copy number alterations (CNAs) of the SWItch/Sucrose NonFermentable (SWI/SNF) comple...

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Bibliographic Details
Main Authors: Zhiwei Xing, Buhuan Ma, Weiting Sun, Yimin Sun, Caixia Liu
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Hereditas
Subjects:
SWI/SNF complex
Copy number alteration
Immune cell infiltration
Genome instability
Online Access:https://doi.org/10.1186/s41065-021-00203-y

Internet

https://doi.org/10.1186/s41065-021-00203-y

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