Mechanisms underlying the anti-inflammatory effects of Clinacanthus nutans Lindau extracts: inhibition of cytokine production and Toll-like receptor-4 activation

Mechanisms underlying the anti-inflammatory effects of Clinacanthus nutans Lindau extracts: inhibition of cytokine production and Toll-like receptor-4 activation

Clinacanthus nutans has had a long history of use in folk medicine in Malaysia and Southeast Asia; mostly in the relief of inflammatory conditions. In this study, we investigated the effects of different extracts of C. nutans upon lipopolysaccharide (LPS) induced inflammation in order to identify it...

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Bibliographic Details
Main Authors: Chun Wai eMai, Ivan Kok Seng eYap, Mee Teck eKho, Nor Hadiani eIsmail, Khatijah Mohd eYusoff, Khozirah eShaarie, Swee Yee eChin, Swee Hua Erin eLim
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Pharmacology
Subjects:
Anti-Inflammatory Agents
Macrophages
Toll-Like Receptor 4
Total flavonoid content
Clinacanthus nutans
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00007/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00007/full

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