The Heterochronic Gene lin-14 Controls Axonal Degeneration in C. elegans Neurons

The Heterochronic Gene lin-14 Controls Axonal Degeneration in C. elegans Neurons

The disproportionate length of an axon makes its structural and functional maintenance a major task for a neuron. The heterochronic gene lin-14 has previously been implicated in regulating the timing of key developmental events in the nematode C. elegans. Here, we report that LIN-14 is critical for...

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Bibliographic Details
Main Authors: Fiona K. Ritchie, Rhianna Knable, Justin Chaplin, Rhiannon Gursanscky, Maria Gallegos, Brent Neumann, Massimo A. Hilliard
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Cell Reports
Subjects:
LIN-14
axonal degeneration
axonal embedment
epidermis
hypodermis
C. elegans
heterochronic gene
mechanosensory neurons
motor neurons
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717312251

Internet

http://www.sciencedirect.com/science/article/pii/S2211124717312251

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