TraFo-CRISPR: Enhanced Genome Engineering by Transient Foamy Virus Vector-Mediated Delivery of CRISPR/Cas9 Components

TraFo-CRISPR: Enhanced Genome Engineering by Transient Foamy Virus Vector-Mediated Delivery of CRISPR/Cas9 Components

The adaptation of CRISPR/Cas technology for use in mammals has revolutionized genome engineering. In particular with regard to clinical application, efficient expression of Cas9 within a narrow time frame is highly desirable to minimize the accumulation of off-target editing. We developed an effecti...

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Bibliographic Details
Main Authors: Fabian Lindel, Carolin R. Dodt, Niklas Weidner, Monique Noll, Fabian Bergemann, Rayk Behrendt, Sarah Fischer, Josephine Dietrich, Marc Cartellieri, Martin V. Hamann, Dirk Lindemann
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253119303026

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http://www.sciencedirect.com/science/article/pii/S2162253119303026

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