High Frequency of Fusion Gene Transcript Resulting From t(10;11)(p12;q23) Translocation in Pediatric Acute Myeloid Leukemia in Poland

High Frequency of Fusion Gene Transcript Resulting From t(10;11)(p12;q23) Translocation in Pediatric Acute Myeloid Leukemia in Poland

11q23/MLL rearrangements are frequently detected in pediatric acute myeloid leukemia. The analysis of their clinical significance is difficult because of the multitude of translocation fusion partners and their low frequency. The presence of t(10;11)(p12;q23) translocation was previously identified...

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Main Authors: Teofila Ksiazek, Malgorzata Czogala, Przemyslaw Kaczowka, Beata Sadowska, Katarzyna Pawinska-Wasikowska, Mirosław Bik-Multanowski, Barbara Sikorska-Fic, Michał Matysiak, Jolanta Skalska-Sadowska, Jacek Wachowiak, Anna Rodziewicz-Konarska, Alicja Chybicka, Katarzyna Muszynska-Rosłan, Maryna Krawczuk-Rybak, Dominik Grabowski, Jerzy Kowalczyk, Lucyna Maciejka-Kemblowska, Elzbieta Adamkiewicz-Drozynska, Wojciech Mlynarski, Renata Tomaszewska, Tomasz Szczepanski, Joanna Pohorecka, Grazyna Karolczyk, Agnieszka Mizia-Malarz, Katarzyna Mycko, Wanda Badowska, Karolina Zielezinska, Tomasz Urasinski, Irena Karpinska-Derda, Mariola Woszczyk, Małgorzata Ciebiera, Monika Lejman, Szymon Skoczen, Walentyna Balwierz
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Pediatrics
Subjects:
acute myeloid leukemia
11q23/KMT2A rearrangements
MLL rearrangements
children
risk stratification
treatment results
Online Access:https://www.frontiersin.org/article/10.3389/fped.2020.00278/full

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https://www.frontiersin.org/article/10.3389/fped.2020.00278/full

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