Hsp90-downregulation influences the heat-shock response, innate immune response and onset of oocyte development in nematodes.

Hsp90 is a molecular chaperone involved in the regulation and maturation of kinases and transcription factors. In Caenorhabditis elegans, it contributes to the development of fertility, maintenance of muscle structure, the regulation of heat-shock response and dauer state. To understand the conseque...

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Bibliographic Details
Main Authors: Julia Eckl, Siyuan Sima, Katrin Marcus, Claudia Lindemann, Klaus Richter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5659845?pdf=render