QSAR STUDIES ON DERIVATIVES OF QUINAZOLINE-4(3H)-ONES WITH ANTICONVULSANT ACTIVITIES

QSAR STUDIES ON DERIVATIVES OF QUINAZOLINE-4(3H)-ONES WITH ANTICONVULSANT ACTIVITIES

Quantitative structure-activity relationship study was done on some quinazoline-4(3H)-ones derivatives with anticonvulsant activity against maximal electroshock-induced seizure. The quinazoline derivatives used as dataset and their anticonvulsant activity value were obtained from the literature. The...

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Bibliographic Details
Main Authors: Adedirin Oluwaseye, A. UZAIRU, G.A. SHALLANGWA, S.E. ABECHI
Format: Article
Language:English
Published: Universidade Federal de Viçosa (UFV) 2018-07-01
Series:The Journal of Engineering and Exact Sciences
Subjects:
Epilepsy
Quantitative structure activity relationship
Kennard-Stone algorithm
Genetic function algorithm
Quinazolinone ring system
Online Access:https://periodicos.ufv.br/ojs/jcec/article/view/2488

Internet

https://periodicos.ufv.br/ojs/jcec/article/view/2488

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