Benzbromarone, Quercetin, and Folic Acid Inhibit Amylin Aggregation

Benzbromarone, Quercetin, and Folic Acid Inhibit Amylin Aggregation

Human Amylin, or islet amyloid polypeptide (hIAPP), is a small hormone secreted by pancreatic β-cells that forms aggregates under insulin deficiency metabolic conditions, and it constitutes a pathological hallmark of type II diabetes mellitus. In type II diabetes patients, amylin is abnormally incre...

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Bibliographic Details
Main Authors: Laura C. López, Olga Varea, Susanna Navarro, José A. Carrodeguas, Natalia Sanchez de Groot, Salvador Ventura, Javier Sancho
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:International Journal of Molecular Sciences
Subjects:
quercetin
benzbromarone
folic acid
amylin
amyloid
aggregation
type II diabetes
Online Access:http://www.mdpi.com/1422-0067/17/6/964

Internet

http://www.mdpi.com/1422-0067/17/6/964

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