A Role of Intestinal Alkaline Phosphatase 3 (Akp3) in Inorganic Phosphate Homeostasis

A Role of Intestinal Alkaline Phosphatase 3 (Akp3) in Inorganic Phosphate Homeostasis

Background/Aims: Hyperphosphatemia is a serious complication of late-stage chronic kidney disease (CKD). Intestinal inorganic phosphate (Pi) handling plays an important role in Pi homeostasis in CKD. We investigated whether intestinal alkaline phosphatase 3 (Akp3), the enzyme that hydrolyzes dietary...

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Bibliographic Details
Main Authors: Shohei Sasaki, Hiroko Segawa, Ai Hanazaki, Ruri Kirino, Toru Fujii, Kayo Ikuta, Miwa Noguchi, Sumire Sasaki, Megumi Koike, Kazuya Tanifuji, Yuji Shiozaki, Ichiro Kaneko, Sawako Tatsumi, Takaaki Shimohata, Yoshichika Kawai, Sonoko Narisawa, José Luis Millán, Ken-ichi Miyamoto
Format: Article
Language:English
Published: Karger Publishers 2018-09-01
Series:Kidney & Blood Pressure Research
Subjects:
Hyperphosphatemia
CKD-MBD
Phosphate transporter
Online Access:https://www.karger.com/Article/FullText/493379

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https://www.karger.com/Article/FullText/493379

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