Solution NMR Spectroscopy in Target-Based Drug Discovery

Solution NMR Spectroscopy in Target-Based Drug Discovery

Solution NMR spectroscopy is a powerful tool to study protein structures and dynamics under physiological conditions. This technique is particularly useful in target-based drug discovery projects as it provides protein-ligand binding information in solution. Accumulated studies have shown that NMR w...

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Bibliographic Details
Main Authors: Yan Li, Congbao Kang
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Molecules
Subjects:
NMR
drug discovery
hit identification
protein dynamics
protein-ligand interactions
fragment screening
Online Access:https://www.mdpi.com/1420-3049/22/9/1399

Internet

https://www.mdpi.com/1420-3049/22/9/1399

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