N-acylation of ethanolamine using lipase: a chemoselective catalyst

The N-acylation of ethanolamine (2) with various fatty acids 1a–d and esters of fatty acids 1e–h using Candida antarctica B lipase (Novozym® 435) are described and optimum conditions for selective N-acylation rather than O-acylation are also discussed. Microwave assisted solution phase, solid suppor...

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Bibliographic Details
Main Authors: Mazaahir Kidwai, Roona Poddar, Poonam Mothsra
Format: Article
Language:English
Published: Beilstein-Institut 2009-03-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.5.10