An integrated strategy by using target tissue metabolomics biomarkers as pharmacodynamic surrogate indices to screen antipyretic components of Qingkaikling injection

Abstract Traditional Chinese medicine (TCM) treatment can be valuable therapeutic strategies. However, the active components and action mechanisms that account for its therapeutic effects remain elusive. Based on the hypothesis that the components of a formula which exert effect would be measurable...

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Bibliographic Details
Main Authors: Zhixin Zhang, Fang Lu, Haiyu Liu, Huizhen Zhao, Yuehong Liu, Shuang Fu, Meiling Wang, Ziye Xie, Honghong Yu, Zhenghai Huang, Yanling Zhang, Xiaoyan Gao
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05812-0