Two-component system cross-regulation integrates Bacillus anthracis response to heme and cell envelope stress.

Two-component signaling systems (TCSs) are one of the mechanisms that bacteria employ to sense and adapt to changes in the environment. A prototypical TCS functions as a phosphorelay from a membrane-bound sensor histidine kinase (HK) to a cytoplasmic response regulator (RR) that controls target gene...

Full description

Bibliographic Details
Main Authors: Laura A Mike, Jacob E Choby, Paul R Brinkman, Lorenzo Q Olive, Brendan F Dutter, Samuel J Ivan, Christopher M Gibbs, Gary A Sulikowski, Devin L Stauff, Eric P Skaar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3968170?pdf=render