Induction of systemic, mucosal and memory antibody responses targeting Vibrio cholerae O1 O-specific polysaccharide (OSP) in adults following oral vaccination with an oral killed whole cell cholera vaccine in Bangladesh.

Induction of systemic, mucosal and memory antibody responses targeting Vibrio cholerae O1 O-specific polysaccharide (OSP) in adults following oral vaccination with an oral killed whole cell cholera vaccine in Bangladesh.

<h4>Background</h4>Oral cholera vaccine (OCV) containing killed Vibrio cholerae O1 and O139 organisms (Bivalent-OCV; Biv-OCV) are playing a central role in global cholera control strategies. OCV is currently administered in a 2-dose regimen (day 0 and 14). There is a growing body of evid...

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Bibliographic Details
Main Authors: Aklima Akter, Pinki Dash, Amena Aktar, Sultana Rownok Jahan, Sadia Afrin, Salima Raiyan Basher, Al Hakim, Asura Khanam Lisa, Fahima Chowdhury, Ashraful I Khan, Peng Xu, Richelle C Charles, Meagan Kelly, Pavol Kováč, Jason B Harris, Taufiqur Rahman Bhuiyan, Stephen B Calderwood, Edward T Ryan, Firdausi Qadri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007634

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https://doi.org/10.1371/journal.pntd.0007634

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